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. 2017 Feb 14;12(2):e0172193. doi: 10.1371/journal.pone.0172193

Table 1. Distribution of demographic and clinical factors by PON1 Q192R phenotype among in vitro fertilization patients (n = 171).

Factor PON1 Q192R phenotype
QQ (n = 70) QR (n = 73) RR (n = 28)
n % n % n %
Age (years)
 < 35 years old 26 54.2 18 37.5 4 8.3
 ≥ 35 years old 44 35.8 55 44.7 24 19.5
BMI (kg/m2)
 < 25 51 46.4 42 38.2 17 15.5
 25–29 13 31.0 22 52.4 7 16.7
 ≥ 30 6 31.6 9 47.4 4 21.1
Race a, *
 non-Asian 56 48.7 47 40.9 12 10.4
 Asian 7 14.9 25 53.2 15 31.9
Cigarette smoking b
 Never 56 38.4 64 43.8 26 17.8
 Ever 9 47.4 8 42.1 2 10.5
Diagnosis
 Male factor 28 45.2 26 41.9 8 12.9
 Unexplained c 18 37.5 18 37.5 12 25.0
 Female factor-non DOR d 13 43.3 14 46.7 3 10.0
 Female factor-DOR 9 33.3 14 51.9 4 14.8
 PGD-only 2 50.0 1 25.0 1 25.0
COS protocol
 Lupron down regulated 48 41.7 48 41.7 19 16.5
 Antagonist 18 42.9 17 40.5 7 16.7
 Flare 4 28.6 8 57.1 2 14.3

a n = 9 missing values;

b n = 6 missing values;

c includes n = 1 recurrent pregnancy loss;

d includes n = 10 endometriosis, n = 10 tubal factor, n = 7 polycystic ovary syndrome and n = 3 anovulation;

* P < 0.05 for across PON1 Q192R phenotypes.

BMI, body mass index; COS, controlled ovarian stimulation; DOR, diminished ovarian reserve; FF, follicular fluid; PGD, pre-implantation genetic diagnosis.