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. 2017 Feb 14;12(2):e0172193. doi: 10.1371/journal.pone.0172193

Table 3. Multivariable linear regression models of follicular fluid (FF) and serum PON1 activities associated with high-density lipoprotein (HDL) particles (μmol/L), according to PON1 Q192R phenotype.

PON activity Phenotype HDL particles FF a Serum
% change 95% CI % change 95% CI
Low High Low High
Arylesterase activity QQ Large 1.22 * 1.14 1.31 1.11 0.88 1.40
Medium 1.34 * 1.21 1.49 1.14 0.98 1.31
Small 1.64 * 1.46 1.84 0.99 0.89 1.10
QR Large 1.12 * 1.01 1.25 1.25 0.87 1.81
Medium 1.40 * 1.19 1.64 1.24 * 1.02 1.52
Small 1.92 * 1.65 2.24 1.24 * 1.07 1.45
RR Large 1.20 * 1.06 1.35 1.11 0.67 1.83
Medium 1.43 * 1.31 1.56 1.00 0.63 1.58
Small 1.55 * 1.33 1.80 1.30 0.81 2.10
Paraoxonase activity QQ Large 1.13 * 1.04 1.22 1.43 * 1.12 1.81
Medium 1.32 * 1.20 1.46 1.21 * 1.04 1.41
Small 1.70 * 1.53 1.90 1.04 0.93 1.17
QR Large 1.11 * 1.04 1.19 1.41 0.89 2.24
Medium 1.33 * 1.23 1.44 1.32 * 1.02 1.70
Small 1.74 * 1.59 1.91 1.27 * 1.05 1.54
RR Large 1.24 * 1.14 1.36 1.80 * 1.16 2.77
Medium 1.58 * 1.46 1.69 1.25 0.83 1.86
Small 1.57 * 1.37 1.80 1.19 0.78 1.79

NOTE: PON enzyme activities and concentrations of HDL particles were natural log-transformed for the analyses. Models were adjusted for age, body mass index, and cigarette smoking.

a Generalized estimating equations were used to provide robust standard errors;

* indicates P < 0.05; CI, confidence interval.