Table 4. Multivariable linear regression models of follicular fluid (FF) PON1 activities associated with size-specific high-density lipoprotein (HDL) particles (μmol/L), according to PON1 Q192R phenotype.

PON activity	Phenotype	HDL particle size (nm)	n women (n follicles)	% change	95% CI
					Low	High
Arylesterase activity	QQ	9.4	59 (102)	1.25 *	1.07	1.46
	QR	8.3	63 (110)	0.74 *	0.62	0.87
	-	8.0	-	1.10 *	1.03	1.16
	RR	13.0	28 (50)	21.39 *	2.52	181.62
Paraoxonase activity	QQ	9.7	59 (102)	1.23 *	1.09	1.40
	QR	8.0	63 (110)	1.14 *	1.06	1.21
	RR	8.5	28 (50)	1.32 *	1.14	1.52

NOTE: PON activities and concentrations of specific HDL particle sizes were natural log-transformed for the analyses. Models were adjusted for age, body mass index, and cigarette smoking, and generalized estimating equations were used to provide for robust standard errors.

* indicates P < 0.05;

CI, confidence interval.