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. 2016 May 10;7(38):60929–60939. doi: 10.18632/oncotarget.9279

Figure 1. Schematic presentations of the studied genomic region 19q13.3.

Figure 1

Upper panel: Gene locations with HUGO gene nomenclature on the chromosome sub-region 19q13.3 are shown. The arrow length represents the extent of the gene and the arrowhead indicates the transcription direction (From: http://www.ncbi.nlm.nih.gov/)(Adopted time: 2013-10-31). The distributed extent of 39 SNPs related to ERCC2, PPP1R13L, CD3EAP and ERCC1 in current study was 71.654kb. Lower panel: D′ LD map and LD plot of 32 SNPs covering ERCC2 (SNP1~10), PPP1R13L (SNP11~19), CD3EAP (SNP20~25) and ERCC1 (SNP26~32) on chromosome 19q13.3 from this Chinese lung cancer study. SNPs in 3′ to 5′ order as indicated in Table 4. Six blocks were detected by Haploview 4.2. The criteria of block partition were based on 95% confidence interval bounds of D′ values. The digit in the boxes D′ value (e.g. 99 means 0.99; 1 means 0.01; empty boxes means 1.0). Deep red boxes designate strong evidence of LD. Light red boxes designate uninformative. White boxes designate strong evidence of recombination.