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. 2016 Aug 16;7(38):61262–61272. doi: 10.18632/oncotarget.11311

Figure 1. TGF-β1 stimulates type II endometrial cancer cell migration.

Figure 1

(A) KLE and HEC-50 cells were treated without (Ctrl) or with 10 ng/mL TGF-β1 for 24 h and then seeded into transwell inserts for the 24-hour migration assay. Upper panels show representative photomicrographs of migrating cells, while lower panels show summarized quantitative results. (B) KLE and HEC-50 cells were pre-treated with vehicle (DMSO) or SB431542 (10 μM) for 1 h and then treated with 10 ng/mL TGF-β1 for 24 h. After treatment, the levels of cell migration were examined by the transwell migration assay (24 h). Results are expressed as the mean ± SEM of at least three independent experiments and values without common letters are significantly different (P < 0.05).