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. 2016 Aug 18;7(38):61426–61437. doi: 10.18632/oncotarget.11366

Figure 3. Silencing of ICAM2 by siRNA vector promotes cancer cell migration and invasion.

Figure 3

(A) Wound healing assay of ICAM2 siRNA plasmid-transfected cells. Phase contrast images were taken at 0 and 16 h after wounding. Representative images showed increased cell migration to the wounded area in ICAM2 siRNA-transfected HSC4 cells. (B) Cell invasion was measured in a Matrigel invasion assay following stable transduction. The experiments were repeated three times with similar results. Representative images showed increased cell invasion in ICAM2 siRNA-transfected HSC4 cells. Quantification of invasion as a percentage of the control is also shown.