Table 3. Multivariate Cox proportional hazards model for the prediction of ESRD in all UC patients who received different clinical treatments (Yes vs. No).
| UC N (%) | Multivariate-HRs (95% CI)a | UT-UC N (%) | Multivariate-HRs (95% CI)a | B-UC N (%) | Multivariate-HRs (95% CI)a | |
|---|---|---|---|---|---|---|
| Endoscopic treatment of bladder | 20393 (73.4) | 0.94 (0.81-1.10) | 1238 (29.0) | 1.00 (0.79-1.27) | 19105 (88.7) | 0.87 (0.67-1.13) |
| Radical Cystectomy | 2528 (9.72) | 1.17 (0.77-1.77) | 69 (1.62) | 4.86 (2.30-10.3)*** | 2442 (11.3) | 0.86 (0.53-1.39) |
| Segmental ureterectomy | 2139 (8.22) | 1.29 (1.08-1.55)** | 1385 (32.5) | 1.06 (0.83-1.36) | 742 (3.45) | 1.58 (1.19-2.09)** |
| Endoscopic treatment of ureter | 337 (1.30) | 1.23 (0.81-1.86) | 161 (3.78) | 1.23 (0.70-2.17) | 176 (0.82) | 0.93 (0.50-1.76) |
| Ureteral reimplantation | 6753 (26.0) | 2.32 (2.01-2.67)*** | 2331 (54.7) | 1.99 (1.52-2.59)*** | 4380 (20.3) | 2.32 (1.96-2.74)*** |
| Diversion | ||||||
| Conduits | 96 (0.37) | 1.22 (0.45-3.29) | 9 (0.21) | NA | 87 (0.40) | 1.93 (0.70-5.31) |
| Continent Cutaneous Diversions | 676 (2.60) | 0.90 (0.50-1.59) | 27 (0.63) | 0.28 (0.06-1.34) | 645 (2.99) | 1.07 (0.58-1.99) |
| Orthotopic Neobladders | 1370 (5.27) | 0.84 (0.52-1.38) | 21 (0.49) | NA | 1340 (6.22) | 1.12 (0.65-1.93) |
| Nephrouretectomy | 4854 (18.7) | 1.91 (1.59-2.28)*** | 3306 (77.6) | 0.97 (0.72-1.29) | 1508 (7.00) | 2.26 (1.76-2.90)*** |
a
Multivariate model adjusted for age, sex, geographic region, occupation, monthly income, and comorbidities (diabetes, hypertension, coronary heart disease, atrial fibrillation, heart failure, chronic kidney disease, and hyperlipidemia).
NA: UT-UCC patients receiving conduits or orthotopic neobladders had no ESRD incidence.