Table 4. Interaction between CKD, UC, and UC subtype type on the risk for ESRD.
| Number, CSS/CN | Multivariate HR (95% CI)a | Trend p values | ||
|---|---|---|---|---|
| CKD | UC | |||
| No | No | 1644/206870 | 1.00 | <0.0001 |
| Yes | 804/25457 | 3.93 (3.61–4.29)*** | ||
| Yes | No | 185/1266 | 16.5 (14.0–19.4)*** | |
| Yes | 175/560 | 57.6 (48.9–67.8)*** | ||
| CKD | UT-UC | |||
| No | No | 1644/206870 | 1.00 | <0.0001 |
| Yes | 272/4106 | 8.99 (7.84–10.3)*** | ||
| Yes | No | 185/1266 | 14.5 (12.3–17.1)*** | |
| Yes | 58/157 | 71.5 (54.7–93.5)*** | ||
| CKD | B-UC | |||
| No | No | 1644/206870 | 1.00 | <0.0001 |
| Yes | 526/21137 | 3.01 (2.73–3.33)*** | ||
| Yes | No | 185/1266 | 15.7 (13.3–18.4)*** | |
| Yes | 116/400 | 50.6 (41.6–61.6)*** |
a
Multivariate model adjusted for age, sex, geographic region, occupation, monthly income, and comorbidities (diabetes, hypertension, coronary heart disease, atrial fibrillation, heart failure, chronic kidney disease, and hyperlipidemia).