Table 1. Cox proportional hazards regression models in estimating cancer development.

Variables	Overall survival		P
	HR	95%
Univariate analysis
CD73 expression
Positive VS negative	2.472	1.367–4.469	0.003
Gender
Male VS female	1.017	0.512–2.020	0.961
Age
< 60 VS ≥ 60	1.008	0.983–1.033	0.539
Smoking
Yes VS no	0.790	0.378–1.650	0.530
Drinking
Yes VS no	0.910	0.422–1.962	0.811
Tumor stage
3–4 VS 1–2	1.355	1.025–1.791	0.033
Lymph node metastasis
+ VS −	1.676	1.230–2.282	0.001
Clinical stage
3–4 VS 1–2	1.433	1.034–1.986	0.031
Histological type
Poor VS well-moderate	1.312	0.986–1.744	0.062
Multivariate analysis
CD73 expression	2.370	1.306–4.466	0.005
Lymph node metastasis	1.765	1.203–2.348	0.002

CI, confidence interval; HR, Hazard ratio.