Table 5. Blood serum chemistry values in tumor-bearing TBG nanocapsule treated mice^a.

Measure	n	TBG-F7 Mean ± SDb	n	TBG-RNAi-CK2 Mean ± SD	p-valuec
Blood Urea Nitrogen (BUN)	6	22.0 ± 5.3 mg/dL	6	20.5 ± 5.3 mg/dL	0.63
Creatinine	6	0.20 ± 0 mg/dL	6	0.20 ± 0 mg/dL	−
Total Serum Protein (TP)	6	4.55 ± 0.15 g/dL	6	4.60 ± 0.20 g/dL	0.64
Alanine Aminotransferase (ALT)	6	19.8 ± 1.5 U/L	6	23.3 ± 4.1 U/L	0.10
Aspartate Aminotransferase (AST)	5	69.6 ± 11.5 U/L	6	86.3 ± 13.8 U/L	0.06

^aSerum was collected 24 h after fourth nanocapsule injection.

^bSD = standard deviation.

^cComparison of TBG-RNAi-CK2 vs. TBG-RNAi-F7 by t-test assuming unequal variances.