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. 2016 Aug 19;7(38):62208–62223. doi: 10.18632/oncotarget.11403

Figure 3. Knockdown of NEAT1 restrained cell proliferation, migration and invasion and promoted apoptosis of GSCs.

Figure 3

A. ACCK-8 assay was used to determine the effect of NEAT1 on GSC proliferation. B. Quantification of the migration and invasion of NEAT1-knockdown GSCs. Representative images and accompanying statistical plots are presented. C. 3D Spheroid-based tumor migration assays of the effect of NEAT1 expression on GSC migration. Scale bars, 60 μm. D. Flow cytometry analysis of the effect of NEAT1 knockdown on GSCs. Data are presented as the mean ± SD (n=5, each group). *P<0.05 vs. sh-NC group. Scale bars, 20 μm.