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. 2016 Aug 19;7(38):62208–62223. doi: 10.18632/oncotarget.11403

Figure 8. Let-7e inhibited GSC malignant progression by binding to the NRAS 3′-UTR.

Figure 8

A. The CCK-8 assay was used to evaluate the effects of let-7e and NRAS (+) on U87 and U251 cell proliferation. B. Quantification of cell migration and invasion in groups according to let-7e and NRAS (+)-NC expression. Representative images and accompanying statistical plots are presented. C. Migration abilities of GSCs in groups according to let-7e and NRAS (+) expression. Scale bars, 60 μm. D. Flow cytometry analysis of GSCs in groups according to let-7e and NRAS (+) expression. Data are presented as the mean ± SD (n=5, each group). *P<0.05 vs. let-7e+NRAS group. Scale bars, 40 μm.