Table 1. Clinical characteristics of 220 HCC patients according to eIF5B expression level.
Feature | eIF5B | χ2 | p-value | |
---|---|---|---|---|
Low | High# | |||
All cases | ||||
Age, y | 0.948 | 0.330 | ||
>55 | 38 | 45 | ||
≤55 | 72 | 65 | ||
Gender | 0.768 | 0.381 | ||
Male | 98 | 101 | ||
Female | 12 | 9 | ||
HBsAg | 6.370 | 0.012 | ||
Positive | 94 | 105 | ||
Negative | 16 | 5 | ||
HBeAg | 1.592 | 0.207 | ||
Positive | 22 | 15 | ||
Negative | 88 | 95 | ||
AFP, μg/L | 1.986 | 0.159 | ||
Positive | 66 | 76 | ||
Negative | 44 | 34 | ||
Tumor size, cm | 1.819 | 0.177 | ||
>5 | 51 | 61 | ||
≤5 | 59 | 49 | ||
Tumor number | 0.698 | 0.403 | ||
Single | 90 | 85 | ||
Multiple | 20 | 25 | ||
Vascular invasion | 24.958 | 0.000 | ||
Present | 50 | 86 | ||
Absent | 60 | 24 | ||
Tumor Differentiation | 11.859 | 0.001 | ||
I-II | 16 | 2 | ||
III-IV | 94 | 108 |
The median expression level was used as the cut-off. Low eIF5B expression in each of the 110 patients was defined as a value below the 50th percentile. High eIF5B expression in each of the 110 patients was defined as a value above the 50th percentile.
For analysis of correlation between the expressions levels of eIF5B and clinical features, Pearson chi-square tests were used. Results were considered statistically significant at p<0.05.