Table 2. Acute toxicity values for BTR, 5MeBTR and 5ClBTR in aquatic organisms.

Compound	Species	Endpointa	Resultsb	Reference
BTR	Zooplankton
	Daphnia magna	48-h LC50	93.3 (76.3–110.3)	this studyc
	D.magna	48-h EC50	107 (97.1–119)	[34]
	D. magna	48-h EC50	155.4 (154.4–156.5)	[35]
	D.magna	21-d EC10	no effect	[34]
	Cerodaphnia dubia	48-h LC50	102 (86–120)	[36]
	Daphnia galeata	48-h EC50	15.8 (13.6–18.3)	[34]
	D.galeata	21-d EC10	0.97 (0.35–2.70)	[34]
	Fish
	Pimephales promelas	96-h LC50	65 (38–75)	[36]
	Danio rerio	72-h EC50	6.43	[35]
	Algae and plant
	Desmodesmus subspicatus	72-h EC10	1.18 (0.4–3.49)	[34]
	Lemna minor	7-d EC10	3.94 (1.95–7.98)	[34]
5MeBTR	Zooplankton
	D. magna	48-h LC50	50.89 (43.58–58.2)	this study
	D. magna	48-h EC50	51.6 (49.7–53.6)	[34]
	D. magna	21-d EC10	5.93 (3.3–10.7)	[34]
	C. dubia	48-h LC50	79 (69–91)	[36]
	C. dubia	48-h LC50	81.3 (70.3–95.1)	[32,37]
	C. dubia	48-h LC50	18–109 (15–137)	[14]
	D. galeata	48-h EC50	5.58 (7.71–9.55)	[34]
	D. galeata	21-d EC10	0.4 (0.08–1.95)	[34]
	Bacteria
	Vibrio fischeri	15-min EC50	8.7 (8.2–9.2)	[36]
	V. fischeri	15-min EC50	4.25 (4.18–4.35)	[32,37]
	V. fischeri	15-min EC50	6–8 (5–11)	[14]
	Fish
	P. promelas	96-h LC50	22 (18–26)	[36]
	P. promelas	96-h LC50	22 (20.5–23.5)	[32,37]
	P. promelas	96-h LC50	8–65 (8–95)	[14]
	Algae and plants
	Scelenastrum capricornutum	96-h IC25	23.2 (22–24.7)	[32]
	D. subspicatus	72-h EC10	2.86 (1.68–4.85)	[34]
	L. minor	7-d EC10	2.11 (0.29–14.9)	[34]
5ClBTR	D. magna	48-h LC50	28.73 (27.6–29.86)	this study

^a EC_x: Effective Concentration for x% of the organisms, LC_x: Lethal Concentration for x% of the organisms, IC_x: inhibition concentration for x% of the organisms.

^b Results are expressed in mg/L with confidence intervals in parentheses.

^c in bold: 48-h LC₅₀ values obtained in this study for D. magna.