Table 3. Number of annotated up- and down-regulated genes measured by RNA-sequencing in response to 2 mg/L exposure to BTR, 5MeBTR and 5ClBTR.
| BTR | 5MeBTR | 5ClBTR | ||||
|---|---|---|---|---|---|---|
| up | down | up | down | up | down | |
| moltinga | 14 | 3 | 5 | 1 | ||
| 20E | 6 | 1 | 1 | 1 | ||
| development / cell morphogenesis | 5 | 3 | 2 | 12 | 1 | |
| glycan | 1 | 2 | 3 | 1 | ||
| lipid metabolism | 2 | 7 | 1 | 2 | 1 | 2 |
| structural proteins | 4 | 1 | ||||
| protein metabolism | 8 | 4 | 1 | 4 | 2 | |
| energy metabolism | 1 | 2 | 1 | |||
| retinol metabolism | 1 | |||||
| RNA processing and metabolism | 2 | 1 | 1 | |||
| transcription/translation | 3 | 4 | 1 | 4 | 1 | |
| cytoskeleton | 2 | 3 | ||||
| oxidative stress | 2 | 1 | 1 | |||
| ion transport, homeostasis | 6 | 2 | 1 | |||
| Membrane trafficking | 1 | 1 | ||||
| response to drug | 2 | |||||
| immune response | 1 | 1 | ||||
| other functions | 11 | 7 | 4 | 8 | ||
a In bold are the most impacted pathways (i.e., highest number of differentially expressed genes) related to molting and developmental processes.