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. 2017 Feb 14;12(2):e0172116. doi: 10.1371/journal.pone.0172116

Fig 2. Suppression of ELAVL-1/HUR leads to down regulation of GSK3β in vitro and subsequently increased of epithelial albumin clearance.

Fig 2

(A) ELAVL-1/HUR protein expression and suppression in nuclear cell lysate in cells treated with ELAVL-1/HUR siRNA. (B) mRNA and protein expression of GSK3β in cells transfected with siELLAVL-1. Binding (C) and uptake (D) of FITC labelled albumin All experiments were conducted in A549 cells, n 3–4; data represent the mean ± SEM * p< 0.05, ***p<0.001, ****p<0.0001.