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. 2017 Feb 14;12(2):e0172157. doi: 10.1371/journal.pone.0172157

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© 2017 Naito et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — (A) The urinary sodium and potassium excretion ratio, (B) renal nuclear expression of MR, and (C) renal SGK1 gene expression at 16 weeks after a 5/6 nephrectomy in the Control-PF (white bar), CKD-PF (black bar), and CKD-IRPF (gray bar) groups (n = 6 in each group). MR, mineralcorticoid receptor; CREB, cAMP response element binding protein; SGK1, serum and glucocorticoid regulated kinase 1; Control-PF, Sham-operated rats fed a normal pair-feeding diet; CKD-PF, 5/6 nephrectomized rats fed a normal pair-feeding diet; CKD-IRPF, 5/6 nephrectomized rats fed an iron-restricted pair-feeding diet. *p < 0.05 versus the Control-PF group, ^†p < 0.05 versus the CKD-PF group.