Fig. 3.
Increased susceptibility for epileptiform activity in glioma-implanted mice.
(a) Representative traces of epileptiform activity in the ipsilateral (top traces) or contralateral cortices (bottom traces) of sham- and glioma-implanted mice generated in the presence of 5, 7.5, or 10 mM KCl at 1 week or 2 weeks post implantation. (b) The percentage of slices discharging in the ipsilateral cortex (top histogram) or contralateral cortex (bottom histogram) in the presence of 5, 7.5, or 10 mM KCl in sham (black bars) or glioma-implanted mice at 1 week (dark grey bars) or 2 weeks post implantation (light grey bars). n = 5–9 slices, 3–5 mice per experimental group. *Denotes a p value <0.05 determined using a one-way ANOVA.