Fig. 6.
Depolarizing GABAergic signaling in the glioma-implanted mice.
(a) Representative traces of depolarizing GABAergic postsynaptic potentials in the peritumoral cortex of glioma-implanted mice in contrast to hyperpolarizing IPSPs in the contralateral cortex. (b) The percentage of neurons with depolarizing GABAergic postsynaptic potentials is increased in the ipsilateral cortex compared to the contralateral cortex where the majority of IPSPs are hyperpolarizing. n = 11–16 neurons, 6–10 mice per experimental group. *Denotes a p value <0.05 determined using a χ2 test.