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Chemical structure of the peptides used in the study.(a) Chemical structure of the ψMARCKS-Cargo, ψIRS1-Cargo, ψDrp1-Cargo and its derivative peptides. (b) Chemical structure of the ψMARCKS, ψIRS1, ψDrp1 and its derivative peptides. The peptides for the cell based and animal studies were conjugated to TAT47-57 carrier peptide, a short positively charged peptide that is used as a carrier for the delivery of the peptides into the cell, using a Gly-Gly spacer.
