Figure 3. Gene expression levels of immune targets in preterm infants with or without BPD in the first week of life.
Relative gene expression of A) IL-4 unstimulated, B) IL-4 stimulated p=0.02 (no BPD v. severe BPD), and C) TBET/FOXP3 ratio in no BPD (n=16), mild BPD (n=13) and severe BPD (n=6) groups. Groups were compared using unpaired t tests when data were normally distributed, otherwise Mann Whitney U-test was used. When there were significant differences in the initial 2-group comparisons (no BPD v. all BPD), Bonferroni-Holm corrections were used to account for the multiple comparisons (no BPD v. mild BPD, no BPD v. severe BPD), *=p≤0.05.