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. Author manuscript; available in PMC: 2017 May 4.
Published in final edited form as: Pediatr Res. 2016 Nov 4;81(2):384–390. doi: 10.1038/pr.2016.232

Figure 4. Changes in gene expression levels of immune targets over infant age for the first 4 weeks of life in preterm infants with chorio, funisitis, or BPD using Generalized Estimating Equations (GEE) models.

Figure 4

Changes in relative gene expression were determined for A) natural logarithm of RORC (beta=2.50, p=0.04) and B) the natural logarithm of the RORC/FOXP3 ratio (beta=2.51, p=0.001) in no chorio (n=17) (dotted line), maternal chorio (n=9) (solid line) and funisitis (n=9) (long dashed line) groups. Changes in relative gene expression were determined for C) transformed TBET (mild BPD, beta for transformed (TBET)0.25=−0.004, p=0.09; severe BPD, beta for transformed (TBET)0.25=−0.01, p=0.73 and D) transformed stimulated IL-2 (beta for transformed IL-2−0.25=0.62, p=0.04 in no BPD (n=16) (dotted line), mild BPD (n=13) (long dashed line) and severe BPD (n=6) (solid line).