Table 1.
Baseline Characteristics by Medication Condition, Mean (SD) or n (%)
| Placebo (n=12) |
3 mg/day Guanfacine (n=14) |
p | ||
|---|---|---|---|---|
| Age | 36.8 (14.5) | 35.1 (11.3) | 0.73 | |
| Sex | 0.54 | |||
| Female | 5 (41.7) | 5 (35.7) | ||
| Male | 7 (58.3) | 9 (64.3) | ||
| Race | 0.83 | |||
| White | 9 (75) | 11 (78.6) | ||
| Other | 3 (25) | 3 (21.4) | ||
| Education | 0.95 | |||
| ≤ High school | 7 (58.3) | 8 (57.1) | ||
| ≥ College | 5 (41.7) | 6 (42.9) | ||
| Marital Status | 0.84 | |||
| Not married | 9 (75) | 10 (71.4) | ||
| Married | 3 (25) | 4 (28.6) | ||
| Tobacco Use | ||||
| Cigarettes per day | 16.8 (8.2) | 20.0 (8.5) | 0.33 | |
| FTND score*a | 5.2 (2.1) | 5.9 (2.5) | 0.46 | |
| CO level at intake | 27.5 (14.2) | 26.9 (17.8) | 0.92 | |
*
FTND, Fagerström Test for Nicotine Dependence
a
Range: scores ≥ 4 for nicotine dependence.
Note: no difference between groups using chi-square or ANOVA where appropriate.