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. Author manuscript; available in PMC: 2017 May 3.
Published in final edited form as: Pediatr Res. 2016 Nov 3;81(2):376–383. doi: 10.1038/pr.2016.218

Figure 2. The effect of moderate hyperoxia on MMP activity.

Figure 2

fASM cells were exposed to 21% or 50% oxygen for 24 hours. Conditioned media was collected, concentrated, and analyzed via gelatinase zymograph for MMP9 and MMP2 activity. MMP activity in concentrated media was normalized to cellular lysate protein concentration. Both pro- and cleaved MMP9 activity were significantly increased with hyperoxia exposure. MMP2 activity was not changed. Values are means ± SEM from n of 4 samples. * indicates significant difference from 21% O2 control with p<0.05.