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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Anesthesiology. 2017 Mar;126(3):547–560. doi: 10.1097/ALN.0000000000001515

Table 1.

Society Guidelines Recommendations for Treatment of Perioperative Hyperglycemia and Diabetes

Ambulatory Surgery ICU Non-ICU
SAMBA 48 SC rapid-acting insulin analogs are preferred over IV or SC regular insulin
Treatment goal: Intraoperative blood glucose levels <180 mg/dL (10 mmol/L)
ADA/AACE 49 Initiate insulin therapy for glucose >180 mg/dL (10 mmol/L).
Treatment goal: For most patients, target a glucose level between 140–180 mg/dL (7.7-10 mmol/L).
Glucose target between 110–140 mg/dL (6.1-7.7mmol/L) may be appropriate for select patients, if achievable without significant risk for hypoglycemia.
Treatment goal: If treated with insulin, pre-meal glucose targets should generally be <140 mg/dL (<7.7 mmol/L), with random glucose levels <180 mg/dL (10 mmol/L).
ACP 52 Recommends against intensive insulin therapy in patients with or without diabetes in surgical/medical ICUs.
Treatment goal: Target glucose is between 140-200 mg/dL (7.7-11.1mmol/L) in patients with or without diabetes.
Critical Care Society 50 BG >150 mg/dL (8.3 mmol/L) should trigger insulin therapy.
Treatment goal: Maintain glucose <150 mg/dL (8.3 mmol/L) for most patients in ICU.
Endocrine Society 30 Treatment goal: Target premeal blood glucose <140 mg/dL (7.7 mmol/L) and random glucose <180 mg/dL (10 mmol/L).
Higher target glucose <200 mg/dL (11.1 mmol/l) is acceptable in patients with terminal illness and/or with limited life expectancy or at high risk for hypoglycemia.
Society of Thoracic Surgeons 51 Continuous insulin infusion preferred over SC or intermittent IV boluses.
Treatment goal: Recommend glucose <180 mg/dL (10 mmol/L) during surgery, ≤110 mg/dL (6.1 mmol/L) in fasting and pre-meal states.
Joint British Diabetes Societies 53 Initiate insulin therapy for glucose >10 mmol/L (180 mg/dL).
Target blood glucose levels in most patients are between 6 and 10 mmol/L (108–180 mg/dL) with an acceptable range of between 4 and 12 mmol/L (72–216 mg/dL).

SAMBA: Society for Ambulatory Anesthesia; AACE/ADA: American Association of Endocrinologists and American Diabetes Association joint guidelines; ACP: American College of Physicians; ADA: American Diabetes Association; ICU: intensive care unit; IV: intravenous; SC: subcutaneous.