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. 2016 Oct 27;36(3):487–494. doi: 10.1007/s10096-016-2822-6

Table 2.

Causes of death during follow-up, according to liver fibrosis stage

Overall (n = 3474) F0–F3 (n = 2713) F4 (n = 761) p-Value
Death (n = 50) 50 (1.4 %) 34 (1.2 %) 16 (2.1 %) 0.082
Causes n =50 n = 34 n = 16
Liver-related 15 (30) 4 (11.7 %) 11 (68.7) <0.001
Non-AIDS malignancies 10 (19.2) 6 (17.6 %) 4 (25) 0.588
Systemic bacterial infection 7 (13.4) 7 (20.6 %) 0 0.054
Cardiovascular event 6 (9.6) 6 (17.6 %) 0 0.116
Abuse of toxic substances 4 (7.6) 3 (8.8 %) 1 (6.3) 0.792
AIDS-related 3 (5.7) 3 (8.8 %) 0 0.389
Gastrointestinal bleeding* 2 (3.8) 2 (5.9 %) 0 0.771
End-stage renal disease 2 (3.8) 2 (5.9 %) 0 0.771
Suicide 2 (3.8) 1 (3.1 %) 0 0.66

*Gastrointestinal bleeding does not include bleeding from esophageal varices