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. 2016 Dec 7;595(4):1039–1058. doi: 10.1113/JP273302

Figure 9. Store‐operated interactions between TRPC1 and STIM1 do not require PLCβ1.

Figure 9

AC, application of BAPTA‐AM for 10 min induced interactions between TRPC1 and PLCβ1 in rabbit portal vein VSMCs measured using PLA that were reduced by expression of PLCβ1 shRNA1 and shRNA2 sequences, whereas associations between TRPC1 and STIM1 were unaffected (three different preparations; * < 0.05). D and E, BAPTA‐AM‐induced interactions between TRPC1 and PLCβ1 measured using co‐immunoprecipitation were reduced by expression of PLCβ1 shRNA1 and shRNA2 sequences, whereas associations between TRPC1 and STIM1 were unaffected (three different rabbit portal vein cell lysates; * < 0.05).