Figure 2. Resistance indices in the umbilical artery during gestation.

Umbilical artery pulsatility (A) and resistance (B) indices derived from waveforms acquired before and after the surgery in control (open circles, continous black lines), control treated with NAC (open triangles, dashed black lines), IUGR (solid circles, continous red lines) and IUGR treated with NAC (solid triangles, dashed red lines) fetal guinea pigs. Slope quantification of PI (C) and RI (D) changes along gestation in control (open bars) and IUGR (solid bars) with (treated) or without (untreated) anitoxidant treatment. Values expressed as mean ± SEM, ^* P < 0.05 vs untreated control, ^# P < 0.05 vs untreated‐IUGR, ANCOVA. [Colour figure can be viewed at wileyonlinelibrary.com]