Table 1.
Population cohorts | Total number of samples | Wild type | Homo-mutant | Hetero | Failed peaks | Mutant allele frequency | Fisher’s Exact (P-value) (Pak-MT vs. other populations-N) |
Fisher’s Exact (P-value) (Pak-N vs. other populations-N) |
HWE (P-value at 1df) |
---|---|---|---|---|---|---|---|---|---|
Mammary tumor cases | 06 | 2 | 2 | 2 | -- | 0.50 | -- | -- | 0.414 (NS) |
Pakistan | 63 | 20 | 4 | 22 | 17 | 0.33 | 0.333 (NS) | -- | 0.549 (NS) |
France | 24 | 15 | 3 | 3 | 3 | 0.21 | 0.071 (NS) | 0.222 (NS) | 0.008 (S) |
Philippines | 22 | 4 | 0 | 16 | 2 | 0.40 | 0.740 (NS) | 0.432 (NS) | 0.003 (S) |
Brunei | 32 | 18 | 4 | 7 | 3 | 0.26 | 0.163 (NS) | 0.465 (NS) | 0.046 (S) |
Iraq | 32 | 10 | 4 | 17 | 1 | 0.40 | 0.543 (NS) | 0.391 (NS) | 0.437 (NS) |
Oman | 12 | 6 | 0 | 4 | 2 | 0.20 | 0.119 (NS) | 0.772 (NS) | 0.429 (NS) |
South Korea | 4 | 4 | 0 | 0 | 0 | 0 | 0.042 (S) | 0.101 (NS) | -(NS) |
USA | 19 | 10 | 1 | 8 | 0 | 0.26 | 0.163 (NS) | 1.000 (NS) | 0.708 (NS) |
Total | 208 | 87 | 16 | 77 | 28 | 0.30 | 0.201 (NS) | 0.704 (NS) | 0.860 (NS) |
S: Significant, NS: Not-significant, MT: Mammary tumor, and N: Normal. http://www.socscistatistics.com/tests/fisher/Default2.aspx