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. 2017 Feb 7;8:14232. doi: 10.1038/ncomms14232

Figure 8. FPR agonist Cmpd17b reduces cardiac dysfunction and inflammation 4 weeks post MI.

Figure 8

(a) FS, (b) ejection fraction and (c) stroke volume at baseline, and 1 and 4 weeks post MI in sham (n=6 mice, open symbols/bars), vehicle- (n=13, black symbols/bars) and Cmpd17b (n=15, blue symbols/bars), 50 mg kg−1 per day i.p.)-treated mice. #P<0.05, ##P<0.01, ###P<0.01 versus sham; *P<0.05 versus vehicle-treated MI mice on two-way ANOVA with Tukey's post hoc test. Impact on cardiac gene expression 4 weeks post MI in the infarcted LV MI, comparing sham (n=6 mice), vehicle- (n=13) and Cmpd17b (n=15), including (d) Fpr1, (e) Fpr2, (f) CD68 and (g) TNF-α; *P<0.05, **P<0.01, ***P<0.001 on one-way ANOVA with Tukey's post hoc test. Results are expressed as mean±s.e.m.