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. 2017 Feb 7;8:14561. doi: 10.1038/ncomms14561

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Comparison of the void volume changes expected by considering that all void volume of the native protein contributes to the ΔV_Void=−V_Void,N, upon unfolding (triangles) with the volume changes that explicitly take into account the void volume of the unfolded state ensemble ΔV_Void=V_Void,U−V_Void,N (circles).