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. 2016 Dec 5;38(2):223–232. doi: 10.1038/aps.2016.114

Figure 6.

Figure 6

The goodness-of-fit plots of the integrated dose-biomarker-response model: Relationship between population predicted values versus observed tumor volumes of the control group (A), and groups treated with 36 mg/kg (B), 72 mg/kg (C), and 108 mg/kg (D) of ethaselen daily; Relationship between individual predicted values versus observed tumor volumes of the control group (E), and groups treated with 36 mg/kg (F), 72 mg/kg (G), and 108 mg/kg (H) of ethaselen daily; Conditional weighted residuals at different time points of the control group (I), and groups treated with 36 mg/kg (J), 72 mg/kg (K), and 108 mg/kg (L) of ethaselen daily; Conditional weighted residuals at different predicted values of the control group (M), and groups treated with 36 mg/kg (N), 72 mg/kg (O), and 108 mg/kg (P) of ethaselen daily.