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SIRT1 protein expression is increased in the injured cortex of rats exposed to TBI induced by LFP. Injured-side cortices were isolated at 6, 12, 24, 48, and 72 h post-TBI. (A) The expression of SIRT1 and β-actin. (B) Quantification of Western blots for SIRT1. (C) The expression of SIRT1 was determined by immunohistochemical staining post-TBI. β-Actin was used as loading control. *P<0.05 vs sham group. n=6/group.
