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. 2016 Nov 21;38(2):264–276. doi: 10.1038/aps.2016.99

Figure 1.

Figure 1

Synergistic effects of SMI with ADR and PTX in a LoVo colon cancer xenograft model. Mice were intraperitoneally injected with ADR (2 mg/kg, every three days) or PTX (7.5 mg/kg, every three days) with or without SMI (0.01 mL/g, every day) for 13 d. n=7-10. (A) Photographs of tumors from each group excised on d 13. (B) Mouse weight curve during treatment. (C) Tumor growth curve of each group during treatment. (D) The ratio of tumor weight and mouse weight in each group after the mice were sacrificed. (E) Tumor weight inhibition rate at d 13. (F) Tumor volume inhibition rate at d 13. *P<0.05, **P<0.01 vs ADR treated groups. #P<0.05, ##P<0.01 vs the PTX treated group.