Table 1. Summary of In-vivo data from Fig. 5.

Cell line	No. of tumor (n)		Dosing Regimen	Average Tumor Volume (mm3) (Endpoint)		Average Tumor Weight (mg)
	KPT-9274	Placebo		KPT-9274	Placebo	KPT-9274	Placebo
MDA-MB-231	16	20	150 mg/kg PO bidx4	128 + 21.7	515.1 + 81.6	64.2 + 9.6	300.2 + 55.8
MDA-MB-468	8	7	100 mg/kg PO bidx4	398.7 + 41	1053.8 + 76	—	—
SUM159	10	10	150 mg/kg PO bidx4	187 + 33.7	524.2 + 90.2	160.8 + 19	463.1 + 81.1