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. 2017 Feb 9;8:14253. doi: 10.1038/ncomms14253

Table 1. Summary of the efficiency and therapeutic index of the monoamines.

Compounds EC50 (μM) TC50 (μM) Therapeutic index
Histamine 1.4±1 <2 mM <1,500
Clobenpropit 24±2 417±6 17.4
Serotonin 1.3±0.5/113±3 1500±54 1,150/13.3