FIG 5.

Effect of penton base-derived, RGD-containing peptides (4 mM) on HAdV-5 and HAdV-37 infection of (A) and binding to (B) HCE cells. 37-RGD, peptide mimicking RGD-containing loop of HAdV-37 penton base. 37-AAA, RGD-containing loop in HAdV-37 penton base peptide replaced with AAA. GRGDSP, peptide used previously (12) to inhibit HAdV infection of human cells. The results are presented as a percentage of the value for the control (i.e., untreated cells). *, P < 0.05; **, P < 0.01; ***, P < 0.001. n = 3.