Table 1.

Cytotoxicity and direct antiviral activity against HSV-2 of the 50% ethanolic extract prepared from fruits of T. chebula, chebulagic acid, chebulinic acids and acyclovir in Vero cells

Test compounds	aCC50 (μg/ml)	bIC50 (μg/ml)
T. chebula 50% ethanolic extract	409.71 ± 47.70	0.01 ± 0.0002
Chebulagic acid	>200c	1.41 ± 0.51
Chebulinic acid	>200c	0.06 ± 0.002
Acyclovir	351.85 ± 48.80	29.04 ± 1.04

Values in this table represent the mean ± SE of four independent experiments performed in duplicate

^aCC₅₀ was the concentration that showed viability of 50% of the Vero cells

^bIC₅₀ was the concentration that inhibited 50% of HSV-2 activity in direct anti- viral activity assay using Vero cells as host

^c > 95% cells were viable at 200 μg/ml