Table 3.
Summary of biomarker measures of infants in the three study groups
Biomarker (mean ± SE) | Cer | Cer + Fr | M | P (within groups) | P (between groups) | |||
---|---|---|---|---|---|---|---|---|
Before CFs | After CFs | Before CFs | After CFs | Before CFs | After CFs | |||
Urinary F2-Isoprostane | N = 7 | N = 7 | N = 8 | N = 8 | N = 10 | N = 10 | 0.3 | 0.5 (Cer vs M) |
(ng/mg) (n = 25) | 0.45 ± 0.81 | 0.52 ± 0.78 | 0.35 ± 0.47 | 0.41 ± 0.08 | 0.48 ± 0.14 | 0.68 ± 0.12 | 0.5 (Cer vs Cer + Fr) | |
Fecal iron | N = 22 | N = 22 | N = 26 | N = 26 | N = 29 | N = 29 | <0.001* | <0.001* (Cer vs M) |
(Fe g/feces) (n = 77) | 3.9 ± 0.37 | 5.6 ± 0.38 | 3.9 ± 0.32 | 4.7 ± 0.34 | 2.9 ± 0.25 | 3.7 ± 0.25 | 0.014* (Cer + Fr vs M) | |
Fecal ROS | N = 16 | N = 16 | N = 21 | N = 21 | N = 29 | N = 29 | 0.002* | 0.6 (Cer vs M) |
(mmol/l) (n = 66) | 0.024 ± 0.007 | 0.037 ± 0.006 | 0.014 ± 0.003 | 0.031 ± 0.005 | 0.023 ± 0.004 | 0.028 ± 0.003 | 0.3 (Cer vs Cer + Fr) | |
Fecal calprotectin | N = 14 | N = 14 | N = 19 | N = 19 | N = 10 | N = 10 | 0.004* | 0.07 (Cer vs Cer + Fr) |
(mg/g feces) (n = 43) | 111.0 ± 12 | 122.3 ± 13 | 93.73 ± 12 | 154.5 ± 23 | 108.1 ± 11 | 131.9 ± 18 | 0.9 (Cer vs M) |
*: P < 0.05 by repeated measures ANOVA