Table 2.
Fold change gene expression between StHdhQ7/7 and StHdhQ111/111 cells for TGFβ pathway-related genes following microarray analysis.
| Gene ID | Gene name | StHdhQ111/111 vs StHdhQ7/7 fold change | p-value |
|---|---|---|---|
| Smurf2 | Smad specific E3 ubiquitin protein ligase 2 | 1.74 | 2.1 × 10− 13 |
| Tgfβ1 | Transforming growth factor beta 1 | − 1.5 | 2.4 × 10− 14 |
| Tgfβr1 | TGF-β receptor 1 | − 1.2 | 1.6 × 10− 5 |
| Tgfβ2 | Transforming growth factor beta 2 | 1.5 | 1.2 × 10− 14 |
| Tgfβr2 | TGF-β receptor 2 | 3 | 5.2 × 10− 33 |
| Tgfβ3 | Transforming growth factor beta 3 | 3 | 2.0 × 10− 25 |
| Tgfβr3 | TGF-β receptor 3 | 6 | 2.1 × 10− 27 |
| Tgfβi | TGF-β induced protein | 11.4 | 2.1 × 10− 30 |
| Smad1 | Mothers against decapentaplegic homolog 1 | − 1 | 4.5 × 10− 1 |
| Smad2 | Mothers against decapentaplegic homolog 2 | − 1.2 | 7.8 × 10− 9 |
| Smad3 | Mothers against decapentaplegic homolog 3 | 1.27 | 1.20 × 10− 12 |
| Smad4 | Mothers against decapentaplegic homolog 4 | − 1.03537 | 3.9 × 10− 2 |
| Smad5 | Mothers against decapentaplegic homolog 5 | − 1.16 | 1.7 × 10− 9 |
| Smad6 | Mothers against decapentaplegic homolog 6 | 1.6 | 3.27 × 10− 15 |
| Smad7 | Mothers against decapentaplegic homolog 7 | − 1.32277 | 1.69 × 10− 9 |