Table 1.
Baseline Demographics
| Variable | All Patients | No SLBa | Yes SLB or Undecided | P Value |
|---|---|---|---|---|
| No. of patients, No. (%) | 33 | 10 (30.3) | 23 (69.7) | |
| Mean age, y (SD) | 57.8 (12.0) | 53.4 (13.9) | 59.7 (10.9) | .2262 |
| Male sex, No. (%) | 15 (45.5) | 5 (50) | 10 (43.5) | 1.0000 |
| Tobacco use, No. (%) | .5138 | |||
| Never smoker | 14 (42.4) | 5 (50) | 9 (39.1) | |
| Former smoker | 15 (45.5) | 5 (50) | 10 (43.5) | |
| Current smoker | 4 (12.1) | 0 | 4 (17.4) | |
| History of emphysema, No. (%) | 7 (21.2) | 1 (10) | 6 (26.1) | .3968 |
| Respiratory symptoms, % | 100 | 100 | 100 | 1.000 |
| Lung examination findings, No. (%) | ||||
| Crackles | 22 (66.7) | 8 (80) | 14 (60.9) | .4300 |
| Wheeze | 2 (6.1) | 0 | 2 (8.7) | 1.0000 |
| None | 10 (30.3) | 2 (20) | 8 (34.8) | .6822 |
| Exposures, No. (%) | 6 (18.2) | 0 | 6 (26.1) | .1445 |
| Family history of ILD, No. (%) | 4 (12.1) | 2 (20) | 2 (8.7) | .5672 |
| Personal history of collagen vascular disease, No. (%) | 5 (15.2) | 1 (10) | 4 (17.4) | 1.0000 |
| FEV1, % predicted (SD) | 80.8 (18.1) | 80.3 (12.0) | 81.0 (20.5) | .9035 |
| FVC, % predicted (SD) | 72.2 (16.6) b1 unknown |
69.4 (11.1) b1 unknown |
73.3 (18.5) | .4774 |
| Ratio, % (SD) | 83.1 (13.6) | 87.9 (17.2) | 80.9 (12.1) | .2886 |
| Diffusion capacity, % predicted (SD) | 55.4 (19.0) b3 unknown |
49.9 (12.1) b1 unknown |
57.8 (21.1) b2 unknown |
.2105 |
HRCT = high-resolution CT; ILD = interstitial lung disease; SLB = surgical lung biopsy.
a
No SLB includes patients with definitive HRCT diagnosis (n = 4).
b
Missing patient data, number as specified.