Table 2.
HRCT Consensus and Clinician Consensus on TBB and SLB Final Diagnoses with Perceived Need for SLB Based on TBB Evaluation Alone
| Case | HRCT Diagnosis Radiology Consensus |
Clinical-Radiologic Impressiona (Confidenceb) | TBB Pathologic Diagnosis | SLB Pathologic Diagnosis | TBB Final Diagnosisa (Confidenceb) | SLB Final Diagnosisa (Confidenceb) | Get SLB? | Agreement in TBB and SLB Final Diagnoses |
|---|---|---|---|---|---|---|---|---|
| 1 | Definite UIP | 1 (2) | UIP | UIP | 1 (1) | 1 (1) | No | Yes |
| 2 | Probable UIP | 1 (1) | Inadequate | UIP | 1 (1) | 1 (1) | No | Yes |
| 3 | Probable UIP | 1 (1) | UIP | HP vs UIP | 1 (1) | 3 (2) | No | No |
| 4 | Probable UIP | 1 (1) | UIP | UIP | 1 (1) | 1 (1) | No | Yes |
| 5 | Possible UIP/NSIP-like | 2 (2) | UIP | UIP | 1 (1) | 1 (1) | No | Yes |
| 6 | Possible UIP/NSIP-like | 1 (2) | UIP | UIP | 1 (1) | 1 (1) | No | Yes |
| 7 | Possible UIP/NSIP-like | 1 (3) | UIP | UIP | 1 (2) | 1 (2) | No | Yes |
| 8 | HP | 3 (3) | HP | HP | 3 (1) | 3 (1) | No | Yes |
| 9 | Normal | 8 (1) | Organizing pneumonia | Organizing pneumonia | 7 (1) | 7 (1) | No | Yes |
| 10 | Other, non-IIP | 7 (2) | Nondiagnostic | Nondiagnostic | 7 (2) | 7 (2) | No | Yes |
| 11 | Possible UIP/NSIP-like | 1 (2) | Nondiagnostic | UIP | 1 (2) | 1 (1) | Undecided | Yes |
| 12 | Possible UIP/NSIP-like | 1 (2) | Inadequate | UIP | 1 (2) | 1 (1) | Undecided | Yes |
| 13 | Possible UIP/NSIP-like | 2 (2) | Nondiagnostic | Probable HP | 2 (2) | 2 (3) | Yes | Yes |
| 14 | Possible UIP/NSIP-like | 3 (2) | Nondiagnostic | UIP | 1, 2, 3 (3) | 1 (2) | Yes | No |
| 15 | Possible UIP/NSIP-like | 7 (2) | UIP | Chronic bronchiolitis | 1 (2) | 6 (2) | Yes | No |
| 16 | Possible UIP/NSIP-like | 2 (2) | UIP | Eosinophilic pneumonia, NSIP | 1 (2) | 7 (1) | Yes | No |
| 17 | Possible UIP/NSIP-like | 3 (2) | Nondiagnostic | UIP | 3, 1 (3) | 1 (2) | Yes | No |
| 18 | Possible UIP/NSIP-like | 1 (2) | Inadequate | UIP | 1 (2) | 1 (1) | Yes | Yes |
| 19 | Possible UIP/NSIP-like | 2, 3 (3) | HP | HP | 3 (2) | 3 (1) | Yes | Yes |
| 20 | Possible UIP/NSIP-like | 1, 2 (3) | Nondiagnostic | UIP | 1, 2 (3) | 1 (1) | Yes | No |
| 21 | Possible UIP/NSIP-like | 1, 2 (3) | Inadequate | UIP | 1 (3) | 1 (1) | Yes | Yes |
| 22 | Possible UIP/NSIP-like | 1, 2, 3 (3) | Inadequate | HP | 3 (3) | 3 (2) | Yes | Yes |
| 23 | HP | 4, 7 (3) | Nondiagnostic | RB | 7 (3) | 4 (2) | Yes | No |
| 24 | HP | 1, 3 (3) | Nondiagnostic | RB | 3 (3) | 4 (1) | Yes | No |
| 25 | HP | 1, 2, 3 (3) | Inadequate | UIP | 1, 2, 7 (3) | 1 (1) | Yes | No |
| 26 | HP | 3, 4 (3) | Nondiagnostic | Peribronchiolar metaplasia | 3 (3) | 4 (2) | Yes | No |
| 27 | Cryptogenic organizing pneumonia | 7 (3) | HP | Organizing pneumonia | 3, 7 (3) | 7 (1) | Yes | No |
| 28 | Emphysema | 5 (1), 2 (3) | Nondiagnostic | HP | 2 (3) | 4 (1) | Yes | No |
| 29 | Other, non-IIP | 7 (2) | Nondiagnostic | Follicular bronchiolitis | 7 (2) | 6 (1) | Yes | No |
| 30 | No consensus HP, small airways disease, other |
4 (3) | Nondiagnostic | RB | 4 (3) | 4 (1) | Yes | Yes |
| 31 | No consensus DIP, probable UIP, other |
2 (2) | Nondiagnostic | NSIP | 2 (2) | 2 (1) | Yes | Yes |
| 32 | No consensus HP, definite UIP, possible UIP |
1 (2), 3 (3) | Nondiagnostic | UIP | 3 (2) | 1 (1) | Yes | No |
| 33 | No consensus HP, possible UIP/NSIP-like, sarcoid |
1 (3) | UIP | HP | 1 (2) | 3 (1) | Yes | No |
DIP = desquamative interstitial pneumonia; HP = hypersensitivity pneumonitis; IIP = idiopathic interstitial pneumonia; NSIP = nonspecific interstitial pneumonia; RB = respiratory bronchiolitis; SLB = surgical lung biopsy; TBB = transbronchial biopsy; UIP = usual interstitial pneumonia. See Table 1 legend for expansion of other abbreviations.
a
1 = UIP; 2 = NSIP; 3 = HP, 4 = RB ILD/DIP; 5 = emphysema; 6 = bronchiolitis; 7 = other; 8 = normal.
b
Confidence: 1 = definite; 2 = probable; 3 = possible.