Table 2.
Significant hyperactivations for disorder-related versus neutral scenes in patients suffering from social anxiety disorder (SAD) relative to healthy controls (HC) as revealed by small-volume corrected analysis (P ≤ 0.005 uncorrected, and P ≤ 0.05 corrected).
| Region | Lateralization | Talairach coordinates of peak voxel |
Cluster size (mm3) | Maximum t-value | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Insula (BA13) | L | − 37 | 12 | 15 | 403 | 4.275 |
| Precuneus (BA7) | R | 4 | − 53 | 48 | 663 | 4.107 |
| STS (BA13) | R | 46 | − 46 | 19 | 721 | 3.389 |
| STS (BA22) | L | − 61 | − 46 | 15 | 480 | 4.103 |
| STS (BA13) | L | 43 | − 26 | − 5 | 103 | 3.835 |
| IFG (BA45) | R | 36 | 24 | 3 | 799 | 3.526 |
| dmPFC (BA8) | L/R | 5 | 36 | 46 | 1270 | 4.012 |
| dmPFC (BA32) | R | 8 | 20 | 42 | 315 | 3.681 |
| dlPFC (BA9) | R | 46 | 12 | 29 | 97 | 3.053 |
| dlPFC (BA6) | R | 39 | 6 | 46 | 837 | 3.695 |
| dlPFC (BA6) | R | 17 | 3 | 55 | 196 | 3.125 |
Note: STS = superior temporal sulcus; IFG = inferior frontal gyrus; dmPFC = dorsomedial prefrontal gyrus; dlPFC = dorsolateral prefrontal cortex.