Table 2.

Protease inhibitors and human disease (adapted from Quesada et al. 2009)

Inhibitor	Disease
α1 Antitrypsin	Thrombosis, emphysema
A1-Antichymotrypsin	Vascular disease
Kallistatin	Pancreatitis
Angiotensinogen	Hypertension, hypotension
Protein Z-dependent protease inhibitor	Venous thrombosis
Vaspin	Diabetes
Maspin	Cancer progression
Megsin	IgA nephropathy
Antithrombin II	Venous thrombosis
Heparin cofactor II	Venous thrombosis
Plasminogen activator inhibitor 1	Bleeding disorders, myocardial infarction
Pigment epithelium-derived factor	Age-related macular disease