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. Author manuscript; available in PMC: 2017 Sep 2.
Published in final edited form as: J Proteome Res. 2016 Aug 5;15(9):3388–3404. doi: 10.1021/acs.jproteome.6b00601

Figure 7.

Figure 7

Effect of WD on dynamic plasma proteome networks. Unsupervised upstream pathway analysis of proteins with measured turnover rate results from the 2H2O metabolic-labeling experiment revealed that observed expression patterns were significantly associated with the suppression of PPARα. The outer circle of proteins was experimentally measured, where a green color represents a decreased k value and red represents an increased k value in WD compared to that in SD. Note that a gray color indicates no change. The activities of proteins (k-values) at the center were predicted to be activated by the upstream analysis as indicated with red color.