Figure 3.

Mini-dystrophin protein expression. The diaphragm of each rAAV1-CMV-miniDMD-treated animal was harvested in six sections (right and left). Representative images are shown from control (A, H), and treated animal #1 right (B–D) and left (I–K), and animal #2 right (E–G) and left (L–N). All sections showed even and widespread DMD expression. Representative higher magnification images (O, P) indicate the dramatic increase in dystrophin expression observed at the muscular component of the diaphragm of the treated (P) versus the control (O) tissue. Color images available online at www.liebertpub.com/humc