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. 2016 Dec 21;5:2893. [Version 1] doi: 10.12688/f1000research.10414.1

Table 3. One and three-year transplant outcomes by ART regimen °.

N
(%)
Patient survival Death-censored graft
survival
Biopsy-proven acute
rejection
Severe
infection
1y p 3y p 1y p 3y p 1y p 3y p 6m p
Overall 58 91.4 89.7 93.1 89.7 13.8 17.2 26.3
TDF
      Yes 19 89.5 89.5 94.7 94.7 15.8 10.5 31.6
      No * 35 94.3 0.6 91.4 >0.99 91.4 >0.99 85.7 0.4 14.3 >0.99 22.9 0.4 23.5 0.52
NRTI
      Yes 54 92.6 90.7 92.6 88.9 14.8 18.52 26.4
      No 4 75 0.3 75 0.36 100 >0.99 100 >0.99 0 >0.99 0 >0.99 25
NNRTI
      Yes 14 100 100 92.9 92.9 7.14 21.4 7.14
      No 44 88.6 0.32 86.4 0.32 93.2 >0.99 88.6 >0.99 15.9 0.66 15.9 0.69 32.6 0.08
PI
      Yes 33 84.5 81.8 87.9 81.8 21.2 18.2 39.4
      No 25 100 0.06 100 0.03 100 0.12 100 0.03 4 0.12 16 >0.99 8.33 0.01
INSTI
      Yes 24 95.8 95.8 100 100 8.33 8.33 21.7
      No 34 88.2 0.39 85.3 0.38 88.2 0.13 82.4 0.04 17.7 0.45 23.5 0.17 29.4 0.5
Two drug regimens ˆ
NRTI + INSTI 12 100 100 100 100 8.3 8.3 18.1
NRTI + NNRTI 9 100 100 100 100 0 11.1 0
NRTI + PI 23 82.6 0.16 78.3 0.1 86.9 0.41 78.3 0.1 21.7 0.36 21.7 0.65 39.1 0.07
NRTI + other * 21 100 100 100 100 4.8 9.5 10
NRTI + PI 23 82.6 0.11 78.3 0.05 86.9 0.23 78.3 0.05 21.7 0.19 21.7 0.42 39.1 0.04

ART, antiretroviral therapy; INSTI, integrase strand transfer inhibitors; NRTI, nucleoside reverse transcriptase inhibitors; NNRTI, non-nucleoside reverse transcriptase inhibitors; PI, protease inhibitors; TDF, tenofovir disoproxil fumarate.

ºRefers to the ART regimen the patient was discharged home with after the initial transplant hospitalization.

P values correspond to Fisher 's exact test. Numbers in bold represent statistical significance.

As defined previously 4. See main text for details.

ˆRegimens listed here were three most common ART regimens post-transplant in this cohort.

*Includes NRTI + INSTI and NRTI + NNRTI.