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. 2016 Feb 3;54(2):1301–1313. doi: 10.1007/s12035-016-9742-4

Fig. 6.

Fig. 6

Model schema describing novel transcriptional capabilities of TRAFs 2 and 3 in neurons. TRAFs 2/3, p65, and pRNAPolII form part of a transcriptional complex on Icam-1 gene promoter upon CD40L stimulation. TRAF2 recruitment to the nucleus is critical for the monoubiquitination of H2B, a transcription permissive epigenetic modification