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. 2016 Feb 3;54(2):1352–1368. doi: 10.1007/s12035-016-9716-6

Fig. 5.

Fig. 5

Changes in the inferior colliculus of transgenic mice. Representative confocal images shows the expression of NF200 (red) and calbindin (green) in cerebellar sections from P16 WT (a, c) and transgenic (b, d) mice. c, d The brachium of the inferior colliculus (arrow) is profoundly reduced in Tg +/− compared to WT mice. An arrowhead indicates an aberrant tract of white matter fibers in the transgenic cerebellum expanding along the hemilobe that is fused with the anterior medullary velum (AMV). e, f The auditory brainstem response (ABR) waveforms of 3-week-old mice to a click stimulus. Individual responses at 80 dB SPL click are represented. Major waves I–IV are indicated above the peaks. The results show that the amplitude of ABR wave IV is lower, and the latency of ABR waves is prolonged in Tg +/− compared to WT. Scale bar 1000 μm (a, b) and 500 μm (c, d)