Table 1.

Characteristics of Fe₃O₄-based PLGA NPs

	Fe3O4-PLGA	Fe3O4-PLGA-cRGD
Size (nm)	289.5±7.4	368.2±4.5
Polydispersity index	0.077±0.031	0.081±0.058
Zeta potential (mV)	−7.53±0.71	−9.43±0.86
Carrier rate of Fe3O4 (%)	66.02±1.7	64.67±0.9
Carrier rate of cRGD (%)	–	99.93±0.06

Note: The Fe₃O₄-PLGA-cRGD NPs are larger than the Fe₃O₄-PLGA NPs (P<0.05).

Abbreviations: cRGD, cyclic Arg-Gly-Asp; NPs, nanoparticles; PLGA, poly(lactic-co-glycolic acid).